FDA warns against use of Ivermectin for prevention of Covid-19

Ivermectin is used for parasite control for horses in USA

The US Food and Drug Administration on Friday said that people should not use ivermectin to attempt to treat or prevent Covid-19. The drug is typically used to treat parasites, such as lice and scabies.

"There seems to be a growing interest in a drug called ivermectin to treat humans with COVID-19. Ivermectin is often used in the U.S. to treat or prevent parasites in animals. The FDA has received multiple reports of patients who have required medical support and been hospitalized after self-medicating with ivermectin intended for horses," the agency's announcement said on Friday.
The announcement noted that the FDA has not approved ivermectin to treat or prevent Covid-19 in humans and the drug is not an anti-viral medication.

"Taking large doses of this drug is dangerous and can cause serious harm," the announcement said, noting that even levels of ivermectin approved for other uses can interact with other medications, such as blood thinners."You can also overdose on ivermectin, which can cause nausea, vomiting, diarrhea, hypotension (low blood pressure), allergic reactions (itching and hives), dizziness, ataxia (problems with balance), seizures, coma and even death."

The announcement comes just a day after new research published in the medical journal JAMA that found ivermectin did not seem to "significantly improve" the time needed for symptoms to get better among patients with Covid-19.
In January, the National Institutes of Health's Treatment Guidelines Panel said that there is not enough data to recommend for or against the drug to treat Covid-19 patients.

The drug is a cheap medication with anti-inflammatory properties and it seemed to stop the virus from replicating in lab studies -- but more research is needed to determine how the drug performs against Covid-19 in real life.
In the JAMA study based in Cali, Colombia, nearly 500 adults with mild disease who had symptoms for seven days, volunteered to help test the drug. The trial is what's known as a double-blind randomized control trial, the gold-standard of trials.
Half the volunteers received the drug for five days, the other half got a placebo, and standard care. Patients were enrolled in the trial between July 2020 and November 2020 and doctors followed up with them through December.
Get CNN Health's weekly newsletter
Sign up here to get The Results Are In with Dr Sanjay Gupta every Tuesday from the CNN Health team.

At the end of the trial, there were a nearly equal number of adverse events -- mostly headache -- in both groups of volunteers. The patients who got the drug said their symptoms subsided by 10 days. For the group that got the placebo, it was 12 days.
Two days was not considered a "significant" improvement.
"The findings do not support the use of ivermectin for treatment of mild COVID-19," wrote the researchers, based in Colombia. The study adds that larger trials may be needed to better understand if ivermectin provides any other kind of benefit to patients with Covid-19. In this case, the study focused on symptoms and mild disease.

Tags : #Ivermectin #RandomizedTrials #TreatingMildCooronavirusCases #JAMA #FDA #FDANews

About the Author


Team Medicircle

Related Stories

Loading Please wait...

-Advertisements-




Trending Now

Successful Removal of 3.7 KG Large Abdominal Tumor from 14-Year-Old Somalian Girl at KIMS Cuddles HospitalMay 16, 2024
iLEAD Sets a Precedent by Launching a Graphic Anthology Authored by Multimedia, Animation and Graphics Students May 16, 2024
Ramaiah Memorial Hospital Launches Novel Intra-Operative Radiation Therapy (IORT); Achieves significant advancement in Cancer Treatment to Enhance Quality of LifeMay 16, 2024
IIITH Announces Product Management Summer SchoolMay 16, 2024
Çelebi India's Delhi Cargo Terminal Successfully Handles Airbus H125 Helicopter ShipmentMay 16, 2024
Plant-Based Diets and Prostate Cancer: New UCSF Study Shows Promising ResultsMay 16, 2024
National Medical Commission Approves 112 New Medical CollegesMay 16, 2024
Study Suggests That Chemotherapy Results in Physical Decline for Older Women with Breast CancerMay 16, 2024
Google DeepMind's AlphaFold 3: Revolutionizing Drug Discovery with AIMay 16, 2024
Hester Biosciences Ltd reports Consolidated Revenue growth of 18% at Rs. 79.3 crore, EBITDA up 37% to Rs. 16.4 crore and Net Profit up 12% to Rs. 6.40 crore in Q4FY24May 16, 2024
Akshay Tritiya Parna Mahotsav heldMay 16, 2024
IT Minister Sridhar Babu to grace the 10th National Facilities Managers Summit-2024, to be held in the cityMay 15, 2024
Alarming Study Reveals Cancer-Causing Chemicals in Car InteriorsMay 15, 2024
India's Thalassemia Challenge: The Importance of Early Screening and TreatmentMay 15, 2024
The Dangers of Ultra-Processed Foods: A 30-Year Study Raises AlarmsMay 15, 2024
Unique Genetic Risk Factors for Breast Cancer Found in African Ancestry StudyMay 15, 2024
AsiaMedic partners with Sunway to establish new diagnostic imaging centreMay 14, 2024
Kamineni Doctors Successfully Remove Bone Stuck Near Heart in Elderly PatientMay 14, 2024
On International Nurses Day, American Oncology Institute (AOI) launches #TheExtraordinaryCareGiver Campaign as Tribute to Oncology NursesMay 14, 2024
Shiprocket announces Shiprocket Growth Academy to upskill 100,000 Indian MSMEs through eCommerce learningMay 14, 2024