Atezolizumab-Bevacizumab Immunotherapy Breakthrough: Transforming Liver Cancer Treatment in India

▴ Atezolizumab-Bevacizumab
Indian study: Atezolizumab-Bevacizumab combo in uHCC shows promising results, with tumour shrinkage and survival benefits, especially when coupled with early treatment and local radiation therapy.

In a groundbreaking study conducted by the Asian Institute of Gastroenterology (AIG), a promising breakthrough in liver cancer treatment has been unveiled, heralding renewed hope for patients grappling with this formidable disease. The study focused on utilizing the potential of Atezolizumab-Bevacizumab immunotherapy, harnessing the body's immune system to combat cancer cells effectively.

Atezolizumab-Bevacizumab, an immunotherapeutic combination, has demonstrated substantial success in managing unresectable hepatocellular carcinoma (uHCC) in real-world settings. The study involved 67 patients with uHCC, comprising 59 individuals from AIG Hospital, Hyderabad, and 8 from Mahatma Gandhi Medical College, Jaipur. The median age of the patients receiving this combination therapy was 61 years, with a majority being males.

The results of the study are indeed promising. Researchers reported that 12.9 per cent of patients achieved complete resolution of tumours, while 25.8 per cent experienced partial resolution or shrinking of tumours. Furthermore, the disease progression halted in an impressive 66.12 per cent of the patients under examination.

In patients with well-functioning livers, the overall survival span reached an encouraging 21 months. Given that liver cancer is often diagnosed at advanced stages, this breakthrough treatment offers a glimmer of hope for improved survival rates, especially when administered to patients with optimal liver function.

An intriguing finding of the study was the enhanced response rates observed in patients who had undergone local radiation therapy in addition to the Atezolizumab-Bevacizumab combination. This suggests the heightened efficacy of this immunotherapeutic pairing in conjunction with localized radiation treatment.

Dr. Nageshwar Reddy, Chairman and Chief of Gastroenterology at AIG Hospitals, emphasized how liver cancer's dynamics are shifting from hepatitis B as a primary cause to non-alcoholic steatohepatitis (NASH or fatty liver) due to contemporary lifestyle choices. This breakthrough immunotherapy has revolutionized the management of advanced liver cancer, offering a more promising approach beyond traditional oral treatments.

Dr. Ashish Kumar, a Senior Consultant from Sir Gangaram Hospital, Delhi, stressed the significance of Atezolizumab-Bevacizumab as the recommended first-line therapy for advanced liver cancer, especially for patients with preserved liver functions. In a country like India, where liver cancer's incidence remains a significant concern, this therapeutic advancement offers a beacon of hope for patients grappling with this formidable disease.

In conclusion, The study not only signifies a transformative milestone in liver cancer treatment but also underscores the critical importance of regular check-ups for patients with cirrhosis. Early detection and timely intervention with Atezolizumab-Bevacizumab immunotherapy could be pivotal in improving outcomes and enhancing the quality of life for liver cancer patients in India. This breakthrough paves the way for a more optimistic future in the battle against liver cancer.

Tags : #livercancer #AIG #livercancerawareness #radiationtherapy #tumour #immunotherapy #cancerawareness #cancerpatients #medicircle

About the Author

Harsh Rathod

Dont judge a book by its cover- that was just my favourite line . When i am not here, I make music, write poems and learning about the healthcare sector has always been on my mind. So here I am exploring and creating content for you all to read:)

View Profile

Related Stories

Loading Please wait...


Trending Now

Freedom Healthy Cooking Oils distributes Seed Ganesha Idols for an eco-friendly festival September 28, 2023
Sadar Hospital,Ranchi Extends Free Cancer Care through Ayushman Bharat Scheme: A ray of hopeSeptember 28, 2023
Dopamine and Its Impact on Your Brain, Feelings, and EmotionsSeptember 28, 2023
Ayushman Bharat-PMJAY: Transforming Healthcare for Millions in IndiaSeptember 28, 2023
Premature Greying of Hair: preventing in the Indian styleSeptember 28, 2023
Run organised to create awareness for Cerebral PalsySeptember 27, 2023
16 Visually challenged explored Skill Development and Employment opportunities in interactive session at FTCCI September 26, 2023
FUJIFILM India celebrates 125 Digital Mammography Machine Installation milestone at the 3rd edition of 'Together Against Breast Cancer' ConferenceSeptember 26, 2023
AI4Rx, the AI powered medical care platform, announces the launch of MedBeat HealthConnectSeptember 26, 2023
Foetal medicine taking rapid strides to optimise Foetal outcomes!September 26, 2023
NGOs bring access to primary health services between 0-3kms for residents of Slums under Jalpally Municipality in line with the UN SDP and Universal Health Coverage modelSeptember 26, 2023
Oliva Skin & Hair Clinic, launches its 25th Clinic in India and 7th in the city, at Dilsukhnagar!September 26, 2023
Badminton sensation Shashidhar brings honor to Telangana and India by clinching the Silver medal at the BWF World Senior Championship in Korea!September 26, 2023
5 Best Homemade Juices to Drink Every Day for a Healthier YouSeptember 26, 2023
Traditionally, men were seen as more profit-oriented in business, but now women are proving they are equally capable - Rahul Jain, a top Indian business coach.September 25, 2023
4-Year-Old Girl Gets New lease of life at American Oncology Institute (AOI) Hyderabad with Haploidentical Stem Cell Transplantation September 25, 2023
Silver Oaks International Schools to provide succor to the underprivileged through its ‘Silver Oaks Street Store’ initiative!September 25, 2023
Sri Pullela Gopichand addressing freshers at OMC, emphasised on focussing on goals to achieve success! September 25, 2023
Fall Prevention Experience Centre for the Elderly Inaugurated at LVPEISeptember 25, 2023
Your Retina, Your Responsibility: 5 Tips For Maintaining Eye HealthSeptember 25, 2023