The new measures French President Emmanuel Macron announced - which come into force on Friday (October 30) - will mean people have to stay in their homes except to buy essential goods, seek medical attention, or use their daily one-hour allocation of exercise.
People will still be allowed to go to work if their employer deems it impossible for them to do the job from home, and - in a departure from the previous lockdown in March - most schools will remain open, Macron said in his address.
The new measures echo the eight-week lockdown that France enforced in the spring, when hospitalisations and deaths caused by the COVID-19 epidemic reached a peak.
The lockdown was effective at containing the epidemic, but the virus started spreading again after it was relaxed on May 11, and people started congregating again in classrooms, universities, bars and restaurants.
France on Tuesday reported 523 new deaths from coronavirus over the previous 24 hours, the highest daily toll since April, when the virus was at its most severe. Doctors have warned that intensive care units risk becoming overwhelmed.
France's death toll, at over 35,000, is the seventh highest in the world, according to Reuters data.
Earlier this month, Macron announced a night-time curfew in Paris and other big cities, but officials this week acknowledged that measure had proved insufficient to bring down infection rates, requiring a more drastic response.