New Discoveries in Colorectal Cancer: Bacteria’s Role in Colorectal Cancer Development

▴ Bacteria’s Role in Colorectal Cancer Development
The study sheds light on a specific bacterium’s role in shielding tumour cells from cancer-fighting drugs, a finding that could revolutionize therapeutic approaches.

In a shocking discovery, scientists have identified a bacterium that could potentially contribute to the rise in colon or colorectal cancer cases. Published in the prestigious journal Nature, the study sheds light on a specific bacterium’s role in shielding tumour cells from cancer-fighting drugs, a finding that could revolutionize therapeutic approaches and early screening methods for colorectal cancer.

Conducted by researchers from the Fred Hutch Cancer Centre in the US, the study revealed that this particular bacterium was present in 50% of the tumours analysed. The bacterium, known as Fusobacterium nucleatum, is commonly found in the mouth but can travel to the gut and thrive within colon cancer tumours.

The study, which examined colorectal cancer tumours removed from 200 patients, found increased levels of Fusobacterium nucleatum in about 50% of cases compared to healthy tissue. Additionally, stool samples from colon cancer patients contained higher quantities of this microbe compared to samples from healthy individuals.

Dr. Susan Bullman, a cancer microbiome researcher and co-corresponding study author, emphasized the association between colorectal tumours containing Fusobacterium nucleatum and poor patient outcomes. Patients with these tumours often exhibit lower survival rates and prognosis compared to those without the bacterium.

Further analysis revealed that Fusobacterium nucleatum in colorectal tumours consists of two distinct lineages or “clades.” Of these, the Fna C2 subtype displayed genetic traits enabling it to travel from the mouth to the lower gastrointestinal tract, where it promotes cancer growth. The researchers identified 195 genetic differences between these clades, with the Fna C2 subtype significantly enriched in colorectal tumour tissue.

This ground-breaking research not only highlights the potential link between Fusobacterium nucleatum and colorectal cancer but also highlights the importance of understanding the microbiome’s role in cancer development and progression. By identifying specific bacterial strains associated with cancer growth, scientists can develop targeted interventions and treatment strategies to improve patient outcomes.

Moving forward, further research is needed to elucidate the mechanisms by which Fusobacterium nucleatum contributes to colorectal cancer progression. Additionally, exploring preventive measures and early detection methods could aid in mitigating the impact of this bacterium on cancer development.

As scientists continue to discover the complexities of the microbiome and its implications for human health, studies like these lead the way for innovative approaches to cancer prevention, diagnosis, and treatment. By leveraging the power of scientific research and collaboration, we can strive towards a future where colorectal cancer is not only treatable but preventable, ultimately saving lives and improving patient well-being

Tags : #

About the Author

Sunny Parayan

Hey there! I'm Sunny, a passionate writer with a strong interest in the healthcare domain! When I'm not typing on my keyboard, I watch shows and listen to music. I hope that through my work, I can make a positive impact on people's lives by helping them live happier and healthier.

View Profile

Related Stories

Loading Please wait...


Trending Now

Empowering India's Youth: IG Drones & AASSC Launch Drone Skill Program, to Upskill 10M YouthApril 17, 2024
Autonomix Medical Inc. Covered in Benzinga Article Highlighting Innovative Nerve Treatment TechnologyApril 17, 2024
Top 5 online learning platform for learnersApril 17, 2024
Broad-Spectrum RNA Vaccine Breakthrough for Enhanced Virus ProtectionApril 17, 2024
The Impact of Excessive Internet Usage on School Absence: Finnish Study Reveals Key FindingsApril 17, 2024
Uncovering Delhi's Illegal Fertility Centre Operations: Insights from Recent Child Trafficking CasesApril 17, 2024
CarDekho's CSR Arm Girnar Foundation Hosts Health Check-up Camps for Underprivileged Children in Jaipur and GurugramApril 16, 2024
Atal Incubation Centre – Centre for Cellular and Molecular Biology (AIC-CCMB) signs agreement for placement of equipment with Thermo Fisher Scientific to help advance innovation in India April 16, 2024
AVEKSHA, four-day care centres, for the kids of industrial workers inauguratedApril 16, 2024
Nearly a third of the constituencies have zero women candidates in Phase 1 and 2 of LS Elections; reveals The Quantum Hub’s Factsheet April 16, 2024
Emergency Healthcare Provider Medulance Secures $3 Million Series A Funding Led by Alkemi Growth CapitalApril 16, 2024
The Healing Power of Natural Diversity: How Nature Boosts Mental HealthApril 16, 2024
Unveiling Cellular Recycling: How Nutrient-Starved Cells Adapt to Stressful ConditionsApril 16, 2024
Advancing Cancer Care: AIIMS Bhopal’s Workshop on Biomarker Interpretation in Breast CancerApril 15, 2024
10 Powerful Benefits to Diversify Healthcare Advertising ChannelsApril 15, 2024
Understanding Hospital Sink Contamination: Challenges in Fighting Multidrug-Resistant BacteriaApril 15, 2024
Rajasthan’s Swine Flu Situation: Health Department Observes DeclineApril 15, 2024
Is Your Doctor’s Prescription Incomplete ? Insights from Recent ICMR Study Suggests So!April 13, 2024
Ministry of Health Dispels Misinformation on Medicine Price Surge from April 1April 13, 2024
India’s First Indigenous CAR T-Cell Therapy Launched By President Droupadi Murmu: A New Hope in Cancer TreatmentApril 12, 2024