New studies provide reassuring data on menstrual changes after covid-19 vaccination

The latest evidence suggests any changes are short-lived and small compared with natural variation in normal cycles

Many women have reported changes to their periods after a covid-19 vaccination and the US National Institutes of Health has allocated $1.67m for research into a possible connection.

Now two new observational studies provide reassuring data suggesting that any changes are short-lived and small compared with natural variation in normal cycles.

Dr Victoria Male, a reproductive specialist at Imperial College London, looks carefully at these new findings in The BMJ today.

The first study drew on data from 3,959 Americans who logged at least six consecutive cycles on a menstrual cycle tracking app. Of these 2,403 were vaccinated and the remainder acted as a control group.

After accounting for other factors, the first dose of vaccine had no effect on timing of the subsequent period, while the second dose was associated with a delay of 0.45 days. 

Most affected were the 358 individuals who received both doses of the vaccine in the same cycle, experiencing a 2.32 day delay to their next period. Among this group, 11% experienced a change in cycle length of more than 8 days, which is considered clinically significant, compared with 4% in the unvaccinated group. In all groups, cycle lengths returned to normal by two cycles after vaccination.

A second study asked a group of 5,688 Norwegians whether they had experienced specific menstrual changes (such as unexpected breakthrough bleeding or worse than normal period pain) in the cycles before and after each vaccine dose.

The high level of variation in normal cycles is underlined by the initial finding that 38% of participants reported at least one change from normal in pre-vaccination cycles, which increased to 39% after the first vaccine dose and 41% after the second dose. The most commonly reported post-vaccination change was heavier than normal period. 

The findings from both these studies are reassuring: changes to the menstrual cycle do occur following vaccination, but they are small compared with natural variation and quickly reverse, says Male.

But she points out that under the UK vaccination schedule, it is impossible to receive both doses of the vaccine in the same cycle, so the changes observed in the US and Norway do not necessarily occur here.

A study using data from UK users of the same menstrual cycle tracking app as in the US study is expected to clarify this point soon, she notes.

In the meantime, the UK medicines regulator (MHRA) says that current evidence does not support a link between changes to menstrual periods and covid vaccination in the UK, and it continues to advise that anyone noticing a change to their periods that persists over several of cycles, or who has any new vaginal bleeding after the menopause, be treated according to the usual clinical pathways.

Much of the public concern around this issue arises from misinformation that covid-19 vaccines cause female infertility, adds Male. 

Although we already have evidence that this is not the case - and evidence also suggests that infection with covid-19 may reduce sperm count and quality - a deeper understanding of the effects of both infection and vaccination on fertility will enable better counselling of patients for whom this is of particular concern, she writes.

These studies represent a step in the right direction, but there is still much to learn, she says. For example, understanding the way in which post-vaccination menstrual changes occur, determining whether any group is particularly vulnerable so they can be counselled appropriately, and better defining the extent and persistence of these changes.

“The widespread public interest in this topic highlights how pressing concern this is for the public. It’s time we started listening to them,” she concludes.

Tags : #MenstrualCycle #Menstruation #Covid-19 #TheBMJ #MHRA

About the Author


Snehangshu Dasgupta,

Managing Editor
[email protected]

Related Stories

Loading Please wait...

-Advertisements-


Trending Now

8 Extremely deadly symptoms you Need to Know about Herpes Simplex VirusSeptember 30, 2022
8 Extremely deadly symptoms you Need to Know about Herpes Simplex VirusSeptember 30, 2022
Post-abortion diet for faster recovery – Foods to eat and to avoidSeptember 30, 2022
Post-abortion diet for faster recovery – Foods to eat and to avoidSeptember 30, 2022
Post-abortion diet for faster recovery – Foods to eat and to avoidSeptember 30, 2022
Resolute -A digital wellness platform providing Hyper-Personalised holistic solutionsSeptember 30, 2022
World Heart Day 2022 – Eat heart-healthy to keep your heart healthySeptember 29, 2022
Loneliness - A deadly cause of your depression you must knowSeptember 29, 2022
Loneliness - A deadly cause of your depression you must knowSeptember 29, 2022
Loneliness - A deadly cause of your depression you must knowSeptember 29, 2022
Know About PCOS Awareness Month-2022 September 29, 2022
What is long covid and how does it affect the body? September 29, 2022
Calcium is essential for smooth functioning of the body and good bone healthSeptember 28, 2022
World Rabies Day 2022 – Rabies symptoms and standard treatmentSeptember 28, 2022
Drinking Amla water gives health 8 tremendous benefitsSeptember 28, 2022
5 home remedies which increase the pumping of the heartSeptember 28, 2022
Factors that cause frequent constipationSeptember 27, 2022
Here are the 10 shocking signs of Dementia you must be aware ofSeptember 27, 2022
Frozen Shoulder Causes And Solutions September 27, 2022
Frozen Shoulder Causes And Solutions September 27, 2022