http://www.21stcenturyhospitalgownplus.com/

http://www.saranametal.com/

http://allinoneglasgow.co.uk/

http://www.elite-factory-15.fr/

http://www.gba-amateurboxen.de/

http://www.enonetexpo.com/

http://www.josephartist.de/

http://www.kita-strausberg.de/

http://sonispicehelensburgh.co.uk/

http://curryzonecardonald.co.uk/

http://cinnamon-edinburgh.co.uk/

http://cafeasiaglasgow.co.uk/

http://www.bombaydelipaisley.com/

http://rocketmeal.co.uk/

http://pizzanightclydebank.co.uk/

http://top-wok.co.uk/

http://curryhutenfield.co.uk/

http://cafeasia.co.uk/

http://www.pizzanightclydebank.com/

http://www.uk-takeaways.com/

http://www.topwokdeepcut.com/

http://www.balticlub.com/

http://www.curry-hut.net/

http://abdulstakeaway.co.uk/

http://gyros2goclydebank.co.uk/

http://motor-zone.co.uk/

http://www.gyros-2-go.com/

http://grillicious.co.uk/

http://grillicious-glasgow.co.uk/

http://panda-house.co.uk/

http://www.abdulstakeaway.com/

http://www.freddiesfoodclub.com/

http://www.hot-food.net/

http://www.pizza-galaxy.com/

http://tasteofchina.co.uk/

http://cinnamonportobello.co.uk/

http://www.shantandoori.com/

http://www.romafishnchips.com/

http://bombaydelipaisley.co.uk/

http://romafishnchips.co.uk/

http://pizzaclub.co.uk/

http://yaraloungerestaurant.co.uk/

http://tasteofchinacoatbridge.co.uk/

http://www.memoriesofindiagorebridge.com/

http://memoriesofindiaeh23.co.uk/

http://gyros2gog81.co.uk/

http://freddiesknightswood.co.uk/

http://asia-star.co.uk/

http://gyros2gohardgate.co.uk/

http://www.sepia.be/

http://www.strausseeschwimmen.de/

http://www.janstanislawwojciechowski.pl/

http://www.tgaheinemann.de/

http://www.papienbanana.com/

http://www.takeawaysrus.com/

http://thepcexperts.co.uk/

http://london-takeaways.co.uk/

http://shahimanziledinburgh.co.uk/

http://shahimanzil.co.uk/

http://www.shahimanzil.com/

http://freddiesfoodclub.co.uk/

http://fishnspice.co.uk/

http://www.spicestakeaway.com/

http://balticlub.co.uk/

http://www.yaratakeaway.com/

http://www.mexita-paisley.com/

http://pandahouseglasgow.co.uk/

http://pizza-galaxy.co.uk/

http://jef.com.hk/

http://www.turpogoda.ru/

http://www.omashonline.com/

http://www.zum-alten-steuerhaus.de/

http://www.strausseelauf.de/

http://pearlofhongkong.co.uk/

http://www.werk-klopsch.de/

http://www.ctgal.net/

http://www.acehonda.in/

http://www.oberstufenzentrum-mol.org/

http://www.fabrygenphen.com/

http://www.morsteins-neuenhagen.de/

http://www.maerkische-jugendweihe.de/

http://www.planungsbuero-henschel.de/

http://www.gpsrinagar.org/

http://www.herm-elektrik.de/

http://www.hertzelektronik.de/

http://www.militaergefaengnisschwedt.de/

http://www.fahrrad-naumann.de/

http://www.praxis-hebes.de/

http://takeawaysrus.co.uk/

http://www.bienesonline.com/

http://bharatdarshan.co.nz/

http://www.dreammedicine.in/

http://www.espace-moto.com/

http://www.oceanemotos.fr/

http://www.motochoc.com/

http://www.legend-bike.fr/

http://www.japautomoto.com/

http://www.hondamoto-villemomble.com/

http://www.hondamoto-royan.com/

http://www.goussmoto.fr/

http://www.espace-moto50.com/

http://www.hondamoto-ajaccio.com/

http://www.download-skycs.com/

http://www.estetikatrebic.cz/

http://www.sisakoskameleon.hu/

http://www.cms91.com/

http://www.topmoto-honda.com/

http://www.paolimotos.fr/

http://www.moto-jack.com/

http://www.hondamoto-montauban.com/

http://www.hondamoto-chalonsursaone.com/

http://www.honda-schumpp.com/

http://www.yasunaga-p.jp/

http://www.oouchigumi.com/

http://www.job-oshigoto.com/

http://www.poissy-motos.com/

http://www.horizonrc.fr/

http://www.hondamoto-champignysurmarne.com/

http://www.hondamoto-asnieres.com/

http://www.pasquier-motos.com/

http://www.homee.vn/

http://jmspackaging.com.ar/

http://www.avtokruiz59.ru/

http://www.gordonstewart.org/

http://www.bilpos.com/

http://benliogludemir.com.tr/

http://www.wsy.ae/

http://www.evacollegeofayurved.com/

http://www.eurobagno.it/

http://www.compro-oro-italia.it/

http://www.melatonina.net/

http://www.hondamoto-saintmaximin.com/

http://www.hoangminhceramics.com/

http://www.rick-farm.com/

http://www.gms-showroom.com/

http://www.rf-solutions.hu/

http://rutasdelplata.com.uy/

http://www.rentuacar.ua/

http://www.pasiekaambrozja.pl/

http://www.xn--b1alildct.xn--p1ai/

http://rentrolls.com.au/

http://www.souzokupedia.org/

http://www.hometech.tw/

http://www.hojokin-times.com/

http://www.updraft-seo.com/

http://snct.org.uk/

http://www.iseeq.com/

http://www.revizaci.cz/

http://wuttinun.ac.th/

http://www.ferreteriaflorencia.com/

http://www.bourgoin-moto.com/

http://andrologia-pta.com.pl/

http://www.thevichotelkisumu.com/

http://www.j-beads.com/

http://angelflightnz.co.nz/

http://www.odelzhausen.de/

http://www.gerberaltd.com/

http://www.jaluzisan.com/

http://www.nexuscollection.com/

http://www.mutdaithanh.vn/

http://www.moitruongminhhuy.com/

http://www.ozkayalarpaslanmaz.com/

http://www.munkagepmonitor.hu/

http://www.my247webhosting.com/

http://www.opalowy-sklad.pl/

http://www.mobilidadept.com/

http://www.furniturewood.ba/

http://www.motosport.fr/

http://www.thesmokingribs.com/

http://www.fureszaru.net/

http://www.olejnikjurajda.cz/

http://www.medica-brno.com/

http://www.namingbranding.ru/

http://mehrallies.co.tz/

http://www.healthlabgrosseto.it/

http://www.ebike-bausatz.eu/

http://www.deostech.cz/

http://www.danmoravsky.cz/

http://www.ochranakaroserie.cz/

http://www.phukiendonginox.com/

http://www.meijersautomotive.nl/

http://www.imexso.com/

http://www.suntekfilms.cz/

http://www.msvberanov.cz/

http://www.kartaestudentit.al/

http://www.ravenfilms.cz/

http://www.podlahyjihlavsko.cz/

http://www.fulfillth.com/

http://www.hillhouseequestrian.com/

http://www.gradskapivnicacitadela.com/

http://www.angerscheune.org/

http://www.caliente-bar.de/

http://www.capella-amadeus.de/

http://www.heide.cz/

http://www.feminasana.cz/

http://www.ensolled.in/

http://www.fehrmannsa.com/

http://www.landfleischerei-auris.de/

http://www.faistesvacances.be/

http://www.autoservice-doernbrack.de/

http://www.tabakhaus-durek.de/

http://www.oldtimer-strausberg.de/

http://www.imexsocarauctions.com/

http://www.jarospol.com/

http://www.kaslikworkshop.com/

http://www.firefightercpr.com/

http://www.visuallearningsys.com/

http://www.holidayshop.co/

http://www.hanksautowreckers.com/

http://www.piaad12.org/

http://www.htl.vn/

http://www.popycopy.cz/

http://www.impresospichardo.com/

http://www.nodel.cz/

http://www.yanabg.com/

http://www.congtykimoanh.com/

http://www.iteskul.com/

http://www.justogo.in/

http://www.philiphydraulics.net/

http://www.internationaldentalimplantassociation.com/

http://www.indywoodtalenthunt.com/

http://www.ozbiltarim.com/

http://www.jocuri-barbie.org/

http://www.horje.com/

http://www.badicecreamgame.com/

http://www.codepostal.org/

http://www.mesfables.com/

http://www.pescons.vn/

http://www.autotextsms.com/

http://www.riad-amarrakech.com/

http://castlemotel.com.au/

http://www.kemia.info/

http://www.biologia.ws/

http://www.tantaki.hu/

http://www.centrodeformacioncanario.com/

http://www.zolum.com/

http://www.socialdefender.com/

http://www.pepiniere-paravegetal.com/

http://www.sportvector.com/

http://www.skimsu.ru/

http://www.hagroup.ma/

http://www.reparertelephonearles.fr/

http://www.namsontrongdoi.com/

http://www.sjpbv.com/

http://www.rtg-dagamed.pl/

http://www.romet.sk/

http://ipcaworld.co.in/

http://www.devipujakjivansathiseva.in/

http://www.laymissionhelpers.org/

http://www.medicircle.in/

http://www.vangiaphatdeco.com/

http://www.sandravall.com/

http://www.iermimpianti.it/

http://www.eho.coop/

http://www.ieiplastics.com/

http://www.ispms.net/

http://www.istomgames.com/

http://www.isscoachinglucknow.in/

http://www.icbproducts.com/

http://www.rokuhasou.net/

http://ranaassociates.co.in/

http://www.ffnn.nl/

http://www.hieuchuandoluong.com/

http://www.hodstrand.hu/

http://www.gasco.bg/

http://www.infranix.com/

http://www.twcpk.com/

http://www.jktsiam.com/

http://www.snscollegeynr.com/

http://www.aurorabienesraices.com/

http://www.robimynadruki.pl/

http://www.hufaled.com/

http://www.ravenmullan.com/

http://petrolchemical.com.vn/

http://ktorganic.com.vn/

http://www.sonnyvandooren.be/

http://www.indianmoversassociation.com/

http://forincorp.com.hk/

http://www.msn-com.de/

http://www.mineralspa.vn/

http://motospeed.com.vn/

http://sekolahgkps.or.id/

http://www.moviedj.tv/

http://www.koreadj.tv/

http://slin.com.tw/

http://ehongshop.com.tw/

http://www.wawakening.org/

http://e-hong.com.tw/

http://www.tkseal.com/

http://www.ryugu-gp.com/

http://www.oztopraklarotomotiv.com/

http://radioouvinte.com.br/

http://moitruongnamnhat.com.vn/

http://www.elysiumlight.eu/

http://odwodnienia.info.pl/

http://www.nostalgikon.pl/

http://www.eulube.com/

http://www.mamaten.jp/

http://www.dienmayvinhthuan.vn/

http://www.kimcan.ca/

http://www.divadelkoproskoly.cz/

http://www.horcsogfalva.hu/

http://www.xn--12cfje1df4hdl7f1bf2evg9e.com/

http://www.westernirontrailers.com/

http://www.csmotortest.com/

http://www.loveisrael.ru/

http://bertez.com.py/

http://www.didibahini.org/

http://www.xmermer.com/

http://www.gouldamandina.hu/

http://www.lestyankert.hu/

http://www.malackafalva.hu/

http://www.ceramet.pl/

http://humeinn.com.au/

http://www.stolprodex.eu/

http://www.jazzaufildeloise.fr/

http://www.rochelmet.vn/

http://nonxedap.com.vn/

http://www.kiohelmet.com/

http://botcamgaoruby.com.vn/

http://www.aiecvisa.com/

http://sinyetech.com.tw/

http://www.signcraft-drone.com/

http://www.nnieuws.be/

http://www.capcitygym.com/

http://intop.in.ua/

http://www.relaxinn.cz/

http://www.realtyhighvision.com/

http://www.fudeso.vn/

http://www.samata.hu/

http://www.winemex.eu/

http://www.thermexscandinavia.nl/

http://www.patron-tyumen.ru/

http://www.caremex.eu/

http://fengxian.com.tw/

http://www.thermex.eu/

http://www.thermex.dk/

http://imobiliariafelipe.com.br/

http://www.slplastic.com/

http://www.jgtt.cz/

http://www.thermex.es/

http://www.salon-lindenoase.de/

http://www.jezirka-zahrada.cz/

http://www.hefleristvan.hu/

http://www.phaarneutral.de/

http://www.kartaextra.com/

http://www.epccompare.com/

http://www.karenpompa.com/

http://www.jsfl.in/

http://www.singhanialogistics.in/

http://www.sonibooks.com/

http://www.der-pixelmischer.de/

http://www.hegermuehlen-grundschule.de/

http://www.radiologie-strausberg.de/

http://www.fahtara.coffee/

http://www.foto-studio-matte.de/

http://www.thermex.se/

http://www.gosfem.com/

http://www.flobico.com/

http://www.ezautorent.hu/

http://www.thermex.fi/

http://www.puremex.eu/

http://www.thermex.no/

http://www.ingerem.in/

http://www.slpipropack.com/

http://slplastic.co.th/

http://www.fisicontrol.pt/

http://www.tables-multiplication.com/

http://www.ecrire-nombre.com/

http://www.siemxpert.com/

http://www.g-concier.com/

http://www.limepuzzle.com/

http://www.videofen.com/

http://www.ratnaglobal.org/

http://www.greenree.com/

http://www.kama-kowalski.pl/

http://www.colegiosam.mx/

http://www.greenree.in/

http://www.retroplayers.be/

http://www.rooshine.com/

http://www.rusztowania-belchatow.pl/

http://www.hanchoom.com/

http://www.fishingandhuntingheaven.com/

http://www.spbnarcolog.ru/

http://www.integra.lv/

http://www.salon-fontanov.ru/

http://www.ekonordhus.lv/

http://www.akupunktura.lv/

http://www.rybieoko.com/

http://www.ryanhastings.net/

http://www.hmc1979.org/

http://seh-biotech.com.tw/

http://www.sad-po.sk/

http://www.sitirecensiti.it/

http://www.orologiegioiellilameridiana.it/

http://www.rotarybresciaest.org/

http://www.loki-spengler.ch/

http://www.valtrompiaset.it/

http://www.fcmellingen.ch/

http://www.jacarandaspain.com/

http://www.javieririberri.com/

http://www.huebelschraenzer.ch/

http://www.gebruederhuber.ch/

http://www.illinoiscreditunionjobs.com/

http://www.ermatekstil.com/

http://www.iznikdenizorganizasyon.com/

http://www.jotellug.com/

http://www.grilliato-nsk.ru/

http://www.homies.no/

http://www.firstfun.in/

http://www.iekatsujiten.com/

http://www.leasebackconcierge.com/

http://www.jobchan.net/

http://www.eoisantacoloma.org/

http://www.hvszzrt.hu/

http://www.skytower.md/

http://www.valudus.com/

http://www.indigramlabs.org/

http://www.gasthof-boegl.de/

http://hkshya.org.hk/

http://skullbasesurgery.co.uk/

http://snnpqo.com.br/

http://indigoandrose.co.uk/

http://www.ijcsit.org/

http://ermisler.com.tr/

http://www.ellimmo.be/

http://www.hediyecigeldi.com/

http://simpol.com.pl/

http://www.isorite.com/

http://www.siso.dk/

http://www.immobilienplattensee.com/

http://www.eurolike.co/

http://www.oofd.kz/

http://www.hoffgun.com/

http://www.nhatminhland.net/

http://itworks.in.ua/

http://www.fenix-coffee.ru/

http://www.germandailynews.com/

http://www.depoos.com/

http://sgmd.org.tr/

http://niccs.co.jp/

http://www.gptdcinternational.com/

http://www.eko-okna.md/

http://www.forklifttrainingedmonton.com/

http://www.vstel.ru/

http://www.kashiwanakayama-cl.com/

http://www.hathanhpccc.com/

http://www.adtennis.com/

http://www.jsminfotech.com/

http://www.dsprinting.id/

http://www.thehousemediagroup.com/

http://www.manganhoa.com/

http://www.kbcgarden.com/

http://www.mamystore.com/

http://www.pensionod.com/

http://www.pensiimaramures.ro/

http://www.michaelakokesova.cz/

http://www.mikrovlny.cz/

http://www.viswabrahmanaeducationaltrust.com/

http://www.roycehelmet.com/

http://mikona.com.pl/

http://www.mojanajkniha.sk/

http://www.ouremaquinas.pt/

http://iist.com.pk/

http://www.newsanjspa.com/

http://krone-aluminium.com.pl/

http://www.ms-klicanska.cz/

http://www.gaaza.ru/

http://www.broadwaylumber.com/

http://www.concadoro.be/

http://www.photog.ru/

http://www.ambulancesoccasions.com/

http://www.contractcity.ru/

http://nung-chia.com.tw/

http://wuyistar.com.hk/

http://www.continuumintegrated.com/

http://www.aiclearn.com/

http://www.podillya.dentist/

http://www.innopoints.com/

http://www.sobateracota.ro/

http://www.buddhagym.hu/

http://www.royalexporter.com/

http://www.bushman.no/

http://www.joilifemarketing.com/

http://www.muoithanhphat.com/

http://www.noa-world.jp/

http://www.rotaseydisehir.com/

http://www.e-salamander.pl/

http://www.northshorefinefoods.com/

http://www.setkaplastic.ru/

http://www.geo-mir.ru/



Using AI to Predict the Outcome of Aggressive Skin Cancers

▴ DeepMerkel
Researchers have developed AI, called DeepMerkel, which can determine the course and severity of aggressive skin cancers enabling medics to personalise treatment.

January 29th, 2025: In two academic papers, a team of researchers led by Newcastle University demonstrates how Artificial Intelligence can determine the course and severity of aggressive skin cancers, such as Merkel cell carcinoma (MCC). This enhanced clinical decision-making by generating personalised predictions of treatment-specific outcomes for patients and their doctors.

 

The international team combined machine learning with clinical expertise to develop the web-based system called “DeepMerkel” which offers the power to predict MCC treatment-specific outcomes based on personal and tumor-specific features.

 

The team suggests that this system could be applied to other aggressive skin cancers for precision prognostication, the enhancement of informed clinical decision-making, and improved patient choice.  

 

MCC

MCC is a rare but highly aggressive skin cancer. It can be difficult to treat - typically affecting older adults with weakened immune systems who present with advanced disease associated with poor survival.

 

Dr. Tom Andrew, a Plastic Surgeon and CRUK funded PhD student at Newcastle University and first author said; “DeepMerkel is allowing us to predict the course and severity of a Merkel cell carcinoma enabling us to personalise treatment so that patients are getting the optimal management.

 

“Using AI allowed us to understand subtle new patterns and trends in the data which meant on an individual level, we can provide more accurate predictions for each patient.

 

“This is important as in the 20 years up to 2020, the number of people diagnosed with this cancer has doubled and while it is still rare it is an aggressive skin cancer which is increasingly affecting older people.”

 

The research was conducted with Penny Lovat, Professor of Dermato-oncology, Newcastle University, and Dr Aidan Rose, Senior Clinical Lecturer, Newcastle University and Consultant Plastic Surgeon at Newcastle Hospitals NHS Foundation Trust.

 

Dr Rose said; “Being able to accurately predict patient outcomes is critical when guiding clinical decision making. This is particularly important when treating aggressive forms of skin cancer in a complex patient group which typically results in difficult, and sometimes life-changing, choices being made regarding treatment options. The developments we have made using AI allow us to provide personalised survival predictions and inform a patient’s medical team of the optimal treatment.”

 

In two complementary publications in Nature Digital Medicine and the Journal of the American Academy of Dermatologythe team describes how using advanced statistical and machine learning methods they developed the web-based prognostic tool for MCC.

 

Method

In Nature Digital Medicine, the team describes how they employed explainability analysis and the data to reveal new insights into mortality risk factors for the highly aggressive cancer, MCC. They then combined deep learning feature selection with a modified XGBoost framework, to develop a web-based prognostic tool for MCC which they termed DeepMerkel.

 

Analysing the data from nearly 11,000 patients in 2 countries, the researchers describe in the Journal of the American Academy of Dermatology how DeepMerkel was able to accurately identify high-risk patients at an earlier stage of cancer. This allows medics to make more informed decisions about when to use radical treatment options and intensive disease monitoring.

 

Patients first

The team hopes that DeepMerkel will provide better information for patients to make decisions with their medical teams about the best treatment for them as individuals.

 

Dr Andrew added: “With further investment, the exciting next step for our team is to further develop DeepMerkel so that the system can present options to help advise clinicians on the best treatment pathway open to them.”

 

The next step is to integrate the DeepMerkel website into routine clinical practice and broaden the scope of its use into other tumour types.

 

References:

Tags : #

About the Author


Team Medicircle

Related Stories

Loading Please wait...

-Advertisements-




Trending Now

This One Nutrient Could Change How We Treat Hypertension And It's Not What You ThinkApril 16, 2025
The Curtain Call That Saves Your Morning: How Natural Light Prepares the Brain to Wake Up GracefullyApril 16, 2025
Vinayaka Missions Super Speciality Hospital opens in PuducherryApril 16, 2025
Remidio with RetinaRisk to Strengthen AI-Driven Diabetic Retinopathy Screening in India and IcelandApril 15, 2025
The New Fertility Crisis: How Modern Lifestyles Are Impacting Your Chances of ParenthoodApril 15, 2025
The Future of Train Travel: Life-saving Healthcare and Regional Cuisine Now on Every TrainApril 15, 2025
The High Price of Healing: How Soaring Surgery Costs Are Bankrupting Indian FamiliesApril 15, 2025
The Price of Survival: Are We Trading Longevity for Disability?April 15, 2025
2,800 Beds. 26 Hospitals. One Vision: Inside the Ujala-Amandeep Power MoveApril 15, 2025
Can Strength Training Rewrite Your Genes? Link Between Muscle Power and Diabetes Prevention.April 15, 2025
Ultra-Processed, Ultra-Powerful: How Modern Food Hijacks Your MindApril 15, 2025
Is Your Health at Risk? The Secret Link Between a Common Parasite and Cervical CancerApril 15, 2025
The Face That Freezes Her Gaze: Why Women Can’t Ignore a Crying InfantApril 15, 2025
Can a Sound Wave Fix Nausea on the Go? A New Hope for Motion Sickness SufferersApril 15, 2025
Gut Instincts, Clear Minds: How Good Bacteria Are Quietly Healing Your MoodApril 15, 2025
When Your Sleep Betrays You: A Deep Dive Into the Nightmare LoopApril 15, 2025
More than 1000 St. George's University Students Secure US Residencies in 2025 MatchApril 15, 2025
Gender justice and health equity are inextricably linked but are programmes linked?April 15, 2025
Berberine Ursodeoxycholate (HTD1801) Consistently Demonstrates Comprehensive Benefits for Patients with Type 2 Diabetes Mellitus, Approaching NDAApril 15, 2025
78% of Indian Youth Embrace Responsibility for Their Healthcare, Burson Global Gen Z ReportApril 14, 2025