Merck, known as MSD outside the United States and Canada, today announced Week 96 data from the Phase 2b trial (NCT03272347) evaluating the efficacy and safety of islatravir, the company’s investigational oral nucleoside reverse transcriptase translocation inhibitor (NRTTI), in combination with doravirine (PIFELTR), in treatment-naïve adults with HIV-1 infection.
“Our commitment to medical advances in HIV can be seen in the important data we are presenting at HIV Glasgow 2020, including islatravir’s potential for use in combination with doravirine as a once-daily, two-drug treatment. In addition, we are presenting data on MK-8507, which is advancing to Phase 2 investigations in combination with islatravir as a once-weekly oral regimen,” said Dr. Joan Butterton, vice president, infectious diseases, Global Clinical Development, Merck Research Laboratories. “We continue to pursue new methods for treating HIV, as shown by our growing body of clinical research, and we look forward to sharing new data from our ongoing, global Phase 3 clinical trials for islatravir with doravirine in the future.”